动物冠状病毒感染特征与跨种传播研究进展

目的 总结动物冠状病毒感染特征及其跨种传播机制,为防治动物源性冠状病毒导致的新发传染性疾病提供参考.方法 以"冠状病毒"、"动物"、"感染"、"跨种传播"为主题词检索中国知网、万方数据库、PubMed数据库,检索日期截至2020年6月30日,共检索到中文文献910篇,英文文献1 374篇,排除重复文献与非相关研究后对1...

Advances in the characteristics of zoonotic coronaviruses infection and its cross-species transmission

To summarize the characteristics of zoonotic coronaviruses infection and its cross-species transmission mechanisms,and to provide references for the prevention of emerging infectious diseases caused by zoonotic coronaviruses. Methods ‘Coronavirus’, ‘animal’, ‘infection’ and ‘cross-species transmission’ were used as subject words to search CNKI, WanFang Data, PubMed database by the end of June 30, 2020. A total of 910 Chinese publications and 1374 English publications were searched. After excluding duplicate and irrelevant studies, 156 publications were summarized. Results Zoonotic coronaviruses have a wide range of hosts and can cause diverse clinical symptoms. Mutation and recombination play an important role in the process of its cross-species transmission. Conclusion It is necessary to reinforce the research on the monitor of zoonotic coronaviruses and pay close attention to the variation of spike protein. Further research on the mechanisms of cross-species transmission may still be needed.