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Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function
Affiliation:1. Division of Gastroenterology, Hepatology and Nutrition, Boston Children’s Hospital, Boston, MA 02115, USA;2. Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA;3. Department of Pathology, Brigham and Women’s Hospital, Boston, MA 02115, USA;4. Center of Neurological Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA;5. Division of Gastroenterology, Hepatology, and Nutrition, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada;6. Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA;7. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA;8. Laboratory of Pediatric Gastroenterology, Erasmus Medical Center-Sophia Children’s Hospital, 3000 CA Rotterdam, the Netherlands;9. Department of Pediatrics, Erasmus Medical Center-Sophia Children’s Hospital, 3000 CA Rotterdam, the Netherlands;10. Pediatric Immunology Service, Edmond and Lily Safra Children’s Hospital, Sheba Medical Center, Tel Hashomer 52661, Israel;11. Division of Pediatric Gastroenterology and Nutrition, Edmond and Lily Safra Children’s Hospital, Sheba Medical Center, Tel Hashomer 52661, Israel;12. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel;13. Department of Pediatric Hematology and Oncology, Hannover Medical School, 30625 Hannover, Germany;14. Department of Gastroenterology, Children’s National Medical Center, Washington, D.C. 20010, USA;15. Division of Pediatric Hematology and Oncology, University of Michigan, Ann Arbor, MI 48109, USA;16. Hospital das Clínicas, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 30130-100, Brazil;17. Division of Gastroenterology, McMaster Children’s Hospital, West Hamilton, Ontario L8N 3Z5, Canada;18. Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA;19. Department of Pathology, Harvard Medical School, Boston, MA 02115, USA;20. Faculty of Life Sciences, University of Manchester, Manchester M13 9PL, UK;21. Dr von Hauner Children’s Hospital, Ludwig-Maximilians-University, 80337 Munich, Germany;22. Division of Gastroenterology, Brigham and Women’s Hospital, Boston, MA 02115, USA;23. interNational Early Onset Paediatric IBD Cohort Study (NEOPICS)
Abstract:
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