| 黎族地中海贫血患者血清促红细胞生成素和转铁蛋白受体水平的研究 |
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| 引用本文： | 姚红霞,陈志斌,丁毅鹏. 黎族地中海贫血患者血清促红细胞生成素和转铁蛋白受体水平的研究[J]. 中国实验血液学杂志, 2002, 10(5): 483-484 |
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| 作者姓名： | 姚红霞 陈志斌 丁毅鹏 |
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| 作者单位： | 1. 海南医学院附属医院血液科,海口,570102
2. 海南省工人医院,海口,570102 |
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| 基金项目： | 国家自然科学基金资助项目编号 3976 0 0 2 6 |
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| 摘 要： | 为研究地中海贫血患者与血清可溶性转铁蛋白受体(sTfR)和红细胞生成素(EPO)的关系，并估计地中海贫血骨髓红系增生程度，应用酶联免疫法检测50例地中海贫血患者和50例正常人对照的sTfR和EPO水平：结果显示，β—重型地中海贫血患者血清EPO和sTfR水平均明显高于正常对照组(P＜0.05)，而轻型患者与正常人无显著差别。结论：黎族地中海贫血患者血清中EPo和sTfR水平升高与地中海贫血的类型有关。
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| 关 键 词： | 黎族 地中海贫血症 促红细胞生成素 转铁蛋白受体 血清 |
Serum Levels of Erythropoietin and Transferrin Receptor in Thalassemia of the Li Nationality |
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| YAO Hong Xia,CHEN Zhi Bin,DING Yi Peng. Serum Levels of Erythropoietin and Transferrin Receptor in Thalassemia of the Li Nationality[J]. Journal of experimental hematology, 2002, 10(5): 483-484 |
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| Authors: | YAO Hong Xia CHEN Zhi Bin DING Yi Peng |
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| Affiliation: | Department of Hematology, The Affiliated Hospital of Hainan Medical College, Haikou 570102, China. dypyhx@public.hk.hi.cn |
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| Abstract: | immunosorbent To determine serum EPO and soluble transferrin receptor (sTfR) level and to assess the degree of erythropoietic proliferation in patients with thalassemia of Li nationality, 50 cases and 50 normal individuals were studied. Enzyme-linked immunosorbent assay was used for EPO and sTfR. Results showed that serum EPO and sTfR levels in beta-thalasemia major patients were significantly higher than those in normal control group, and no significant difference in beta-thalassemia minor cases with those in control. It is concluded that increase of serum EPO and sTfR level is related to the type of thalassemia. |
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| Keywords: | Li nationality thalassemia erythropoietin transferrin receptor |
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