2010-2013年苏州大学附属常熟医院抗肿瘤药应用分析

目的：了解苏州大学附属常熟医院（以下简称“我院”）抗肿瘤药的应用情况和趋势。方法：采用回顾性方法，对我院2010-2013年抗肿瘤药的采购金额、用药频度（DDDs）等进行统计、分析。结果：我院抗肿瘤药采购金额和DDDs均呈逐年上升趋势，年均复合增长率分别为26．31％和23．88％。采购金额排序居前3位的类别是其他类、抗肿瘤植物类和抗代谢药，三者构成比之和〉70％。DDDs排序居前2位的是抗代谢类和抗肿瘤激素类，居第3位的是其他类或中药类，三者构成比之和〉85％。奥沙利铂、香菇多糖、多西他赛、艾迪、紫杉醇和培美曲塞是主要使用品种。结论：我院抗肿瘤药应用现状基本符合当前我国肿瘤治疗的趋势，医院抗肿瘤药的用量持续增长，传统中药具有一定的临床应用价值，靶向治疗将成为肿瘤治疗的热点。

Utilization of Antitumor Drugs in Changshu Hospital Affiliated to Soochow University during 2010-2013

OBJECTIVE：To probe into the status quo Hospital Affiliated to Soochow University（ ＂our hospital＂） and tendency of the utilization of antitumor drugs in Changshu during 2010-2013 period. METHODS ： By retrospective study, the utilization of antitumor drugs in our hospital during 2010-2013 period were analyzed statistically with regard to consumption sum and DDDs etc. RESULTS： The consumption sum and DDDs of antitumor drugs in our hospital increased year by year with compound annual growth rate（CAGR） of 26. 31% and 23.88%, respectively. The top three antitumor drugs ranked by consumption sum were the other class of antitumor drugs, antitumor plants and antimetabolites, and the constituent ratio of the above three was over 70%. Antimetabolites and antitumor hormones dominated the top two places in terms of DDDs, followed by the other class of antitumor drugs or traditional Chinese medicine ranked third place, and the constituent ratio of the above three was over 85%. Oxaliplatin, lentinan, docetaxel, Aidi, paclitaxel and pemetrexed were the dominant antitumor drugs. CONCLUSIONS： The use of antitumor drugs in our hospital is basically consistent with the medication tendency of antitumor drugs in our country. The consumption amount of antitumor drugs in our hospital has been increasing, and traditional Chinese medicine has certain clinical application value. Targeted therapy is expected to become the focus in oncotherapy.