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氟代脱氧葡萄糖与氨基酸PET在脑肿瘤中的对比研究
引用本文:蔡莉,李彦生. 氟代脱氧葡萄糖与氨基酸PET在脑肿瘤中的对比研究[J]. 国际放射医学核医学杂志, 2005, 29(1): 10-14
作者姓名:蔡莉  李彦生
作者单位:300052,天津医科大学总医院PET-CT中心;300052,天津医科大学总医院PET-CT中心
摘    要:脑肿瘤细胞生长速率加快,能量代谢、氨基酸转运和蛋白质合成旺盛。联合18F-FDG与11C-MET的PET,比单一显像剂更有助于脑肿瘤的组织学分级、术后复发和疗效评价。11C-MET较18F-FDG能更精确地显示肿瘤扩散范围和轮廓,对制订手术和立体定向放疗计划有重要意义,是常规CT和(或)MRI的有益补充。

关 键 词:18F-氟代脱氧葡萄糖  11C-甲硫氨酸  正电子发射体层显像  脑肿瘤  对比研究
文章编号:1001-098X(2005)01-0010-05
修稿时间:2004-10-09

Comparison of 18F-FDG and amino acid PET imaging in brain tumors
CAI Li,LI Yan-sheng. Comparison of 18F-FDG and amino acid PET imaging in brain tumors[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2005, 29(1): 10-14
Authors:CAI Li  LI Yan-sheng
Abstract:Energy metabolism and amino acid transport and incorporation are important components of the pathophysiology of brain tumors. Combination of 18F-FDG and amino acid, especially 11C-MET is more useful than single tracer in the field of brain tumor grading, differential diagnosis recurrent tumor from radiation necrosis and evaluation of prognosis. In addition, 11C-MET is better than 18F-FDG in delineating tumor boundary, so it can provides more exact information in biopsy localization and planning of radiosurgery.
Keywords:F-fluorodeoxyglucose  11C-methionine  positron emission tomography  brain tumor  comparison study
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