Perspicamides A and B, quinolinecarboxylic acid derivatives from the Australian ascidian Botrylloides perspicuum |
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| Authors: | McKay Matthew J Carroll Anthony R Quinn Ronald J |
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| Institution: | Natural Product Discovery, Eskitis Institute, Griffith University, Brisbane, Queensland, Australia 4111. |
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| Abstract: | Two novel quinoline-2-carboxylic acid derivatives, perspicamides A (2) and B (3), were isolated from the Australian ascidian Botrylloides perspicuum. Extraction of the freeze-dried ascidian with methanol and purification of the extract by C18 MPLC followed by repeated C18 HPLC yielded the new compounds 2 and 3 as well as the known compounds botryllamides A-C (4-6). The structures of 2 and 3 were determined from analysis of 2D NMR spectra. |
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