急性脑梗死SPECT成像及对溶栓治疗指导作用的研究进展

超早期溶栓治疗是急性脑梗死早期治疗的重要方法。溶栓的有效性随时间的延长而降低,而其颅内出血的危险性却持续存在甚或有所增加。因此,合适的影像学检查对急性脑梗死超早期溶栓的准确选择及溶栓并发症的预测至关重要。本文就SPECT在急性脑梗死溶栓治疗领域的临床研究进展进行综述。

Advances in Imaging with SPECT in Acute Cerebral Ischemia and Directions of Thrombolytic Therapy

Thrombolysis-induced reperfusion is a proven therapy for acute ischemic stroke when performed within the first few hours after symptom onset.On average,the benefit of thrombolysis fades with time;however,the risk of cerebral hemorrhage remains constant or increasing.An imaging method for the prediction of hemorrhage after thrombolysis-induced reperfusion would greatly alter the decision process for treatment.It is proved that SPECT can improve the prospective value of brain imaging within 6 hours after the onset of stroke symptoms.In this review,we summerised the general idea of SPECT and its predictive value of imaging after acute cerebral ischemia and giving directions of thrombolytic therapy.