| 槐胺碱对小鼠免疫功能的影响 |
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| 引用本文： | 张佩,李淑华,金英,金丽杰. 槐胺碱对小鼠免疫功能的影响[J]. 中草药, 1996, 27(1): 25-27 |
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| 作者姓名： | 张佩 李淑华 金英 金丽杰 |
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| 作者单位： | 锦州医学院微生物教研室!121001(张佩，李淑华)，锦州医学院药理教研室(金英)，锦州市第二医院药局(金丽杰) |
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| 摘 要： | 观察了槐胺碱（SA）对正常小鼠免疫功能的影响。结果表明：SA15、20mg／kg减低胸腺重量，降低E花环形成率，抑制T淋巴细胞转化，但对脾脏重量无明显影响，也不影响脾脏溶血空斑形成。SA25mg／kg则显著降低胸腺和脾脏重量，降低E花环形成率，抑制T淋巴细胞转化。而各剂量SA均不影响腹腔巨噬细胞吞噬功能。
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| 关 键 词： | 槐胺碱 溶血空斑 E花环 淋巴细胞转化 |
| 收稿时间： | 1994-12-29 |
Effect of Sophoramine on Immune Function of Mice |
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| Zhang Pei,Jin Ying and Jin Lijie. Effect of Sophoramine on Immune Function of Mice[J]. Chinese Traditional and Herbal Drugs, 1996, 27(1): 25-27 |
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| Authors: | Zhang Pei Jin Ying Jin Lijie |
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| Abstract: | The effects of sophoramine (SA) on immune system in normal mice were studied. SA 15. 20mg/kg reduced the weight of thymus,decreased the rate of E rosette,and also suppressed T lymphocyte transformation. The weight and the hemolytic plaque of spleen were not influenced by SA at 15. 20mg/kg. At the dose of 25mg/kg,SA reduced the weight of thymus and spleen,decreased the rate of E rosette and suppressed the T lymphocyte transformation. All of the doses of SA didn' t affect the phagocytotic function of peritoneal macrophage. |
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