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A Meta-analysis of 2-Year Effect After Surgery: Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity and Diabetes Mellitus
Authors:Chengda Zhang  Yuan Yuan  Cuiqiong Qiu  Weidong Zhang
Institution:1. Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
2. Department of Preventive Medicine, Zhengzhou Health School, Zhengzhou, Henan, People’s Republic of China
3. School of Nursing, Guang Dong Food and Drug Vocational College, Guangdong, Guangzhou, People’s Republic of China
4. Department of Epidemiology, School of Public Health, Zhengzhou University, No.100 Kexue Avenue, Zhengzhou, Henan, 450001, People’s Republic of China
Abstract:Literature search was performed for bariatric surgery from inception to September 2013, in which the effects of laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) on body mass index (BMI), percentage of excess weight loss (EWL%), and diabetes mellitus (DM) were compared 2 years post-surgery. A total of 9,756 cases of bariatric surgery from 16 studies were analyzed. Patients receiving LRYGB had significantly lower BMI and higher EWL% compared with those receiving LSG (BMI mean difference (MD)?=??1.38, 95 % confidence interval (CI)?=??1.72 to ?1.03; EWL% MD?=?5.06, 95 % CI?=?0.24 to 9.89). Improvement rate of DM was of no difference between the two types of bariatric surgeries (RR?=?1.05, 95 % CI?=?0.90 to 1.23). LRYGB had better long-term effect on body weight, while both LRYGB and LSG showed similar effects on DM.
Keywords:
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