精神分裂症患者不同状态探究性眼球轨迹运动研究

目的 :比较精神分裂症患者不同状态下探究性眼球轨迹运动的差异及判别分析结果。方法 :应用眼球轨迹运动记录仪测试正常人组 2 2例 ;精神分裂症患者症状显著组 2 6例 ,缓解组 61例 ,慢性组 (阴性症状为主 ) 3 0例 ,并进行组间比较。结果 :正常人对照组为负分 ( -1 2 75 ) ,精神分裂症患者各组均为正分 ;其中症状显著组 1 85 8分 ,症状缓解组 2 3 3 2分 ,慢性组 3 499分。正常对照组与精神分裂症患者各组在眼球轨迹运动各项指标比较其差异均有显著性 (P <0 0 5～ 0 0 1)。显著组和缓解组与慢性组某些指标比较其差异同样有显著性 (P <0 0 5～ 0 0 1) ,但显著组与缓解组所有指标比较其差异均无显著性 (P >0 0 5 )。结论 :探究性眼球轨迹运动对精神分裂症患者诊断可起到一定的辅助作用。反应性探究分 (RSS)可作为精神分裂症特定的生物学指标之一。

Study of Exploratory Eye Tracking Movement on different Status in Schizophrenics

Objestive: To explore the differences of eye tracking movements on different status and the results of discriminate analysis in schizophrenics compared with normal controls Method: Twenty-six schizophrenics with prominent symptoms, 61 in relief, 30 chronic schizophrenics with negative symptoms prominently and 22 normal controls were tested by Eye Movement Recorder-Model IV Results: The results of discriminant analysis showed that schizophrenics got positive scores on several status, the average score were 1 865, 2 332 and 3 499 in patients with prominent symptoms, those in relief and chronic schizophrenics respectively, while normal controls got negative scores (-1 275) The differences of all indices of eye movements between schizophrenic groups and normal control group had statistical significance (p<0 05) The differences between chronic group and the group with prominent symptoms, between chronic group and the group in relief had also statistical significance (p<0 05), but those between the group with prominent symptoms and the group in relief had no significance Conclusion: Explorative eye tracking movement may assist in the diagnosis of schizophrenia and RSS may act as one of biological markers of schizophrenics