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Crystallisation of calcium oxalate dihydrate in normal urine in presence of sodium copper chlorophyllin
Authors:R. Tawashi  M. Cousineau  G. Denis
Affiliation:(1) Faculty of Pharmacy, Hôpital du Sacré-Coeur, University of Montreal, Montreal, Quebec, Canada;(2) Department of Physiology, Hôpital du Sacré-Coeur, University of Montreal, Montreal, Quebec, Canada;(3) Service of Nephrology, Hôpital du Sacré-Coeur, University of Montreal, Montreal, Quebec, Canada;(4) Faculté de Pharmacie, Université de Montréal, C.P. 6128, Succ. "ldquo"A"rdquo", H3C 3J7 Montréal, Québec, Canada
Abstract:Summary A method is described for the growth of calcium oxalate dihydrate in normal urine. Soluble chlorophyllin, at a concentration of 20 mgrg/ml inhibited the crystallisation and the growth kinetics of the dihydrate crystals. The inhibitory capacity of chlorophyllin was compared with previous results. Data obtained suggest that the food and drug colourant chlorophyllin might be useful in the treatment of calcium oxalate stone disease.
Keywords:Inhibitors  Calcium oxalate dihydrate  Growth kinetics  Soluble chlorophyllin  Calcium stones
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