中西医结合治疗SARS疑似患者40例临床观察

目的：观察SARS疑似患者临床症候的改善时间及中西医结合治疗效果。方法：对40例SARS疑似患者临床症候、胸片、舌象进行观察，并给予中西医结合治疗，同时对20例疑似患者进行动态T细胞亚群、血清冠状病毒核酸及抗体测定。结果：40例患者发热、汗出、乏力、干咳等主要症状及舌象均得到明显改善，胸片开始吸收时间为(4．54±2．85)天，明显吸收时间为(7.74±4．68)天。其中20例患者入院时T细胞亚群CD3、CD4、CD8平均值低于正常，入院第3天开始升高，6～10天逐步恢复到正常范围。3例患者发现血清冠状病毒核酸阳性，2例冠状病毒抗体阳性，1例两者同时存在。结论：中西医结合疗法可以改善SARS疑似患者临床症状，调节免疫功能。

Clinical Observation on Treatment of 40 SARS Uncertain Patients with Integrative Traditional Chinese and Western Medicine

OBJECTIVE: To observe the clinic symptom improving time in uncertain SARS patients and the therapeutic effect of integrative Chinese and western medicine (ICWM) in treating SARS. METHODS: The clinic symptoms, chest film and tongue figure of 40 uncertain SARS patients treated with ICWM were observed and T-lymphocyte subsets, serum coronavirus nucleic acid and antibody in 20 patients were tested dynamically. RESULTS: All the symptoms, such as fever, sweating, fatigue, cough without phlegm, etc. were obviously improved after treatment. Lung shadow in chest film began to be absorbed 4.54 +/- 2.85 days, and obviously absorbed 7.74 +/- 4.68 days after treatment. CD3, CD4 and CD8 in 20 patients, which were lower than the normal range when hospitalization, began to increase 3 days later and gradually recovered to the normal in 6-10 days. Serum coronavirus nucleic acid was positive in 3 patients, coronavirus antibody positive in two and both were positive in one. CONCLUSION: ICWM can improve the symptoms and regulate the immune function in uncertain SARS patients.