| 维生素C泡腾片的制备 |
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| 引用本文： | 张丽锋,石秀锦,张淑秋,苏畅.维生素C泡腾片的制备[J].山西医科大学学报,2004,35(1):22-24. |
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| 作者姓名： | 张丽锋 石秀锦 张淑秋 苏畅 |
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| 作者单位： | 1. 山西医科大学药学院临床药学教研室,太原,030001
2. 武警山西总队医院药剂科 |
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| 基金项目： | 山西省教育厅科研基金资助项目 |
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| 摘 要： | 目的 维生素C泡腾片的处方筛选。方法 四种不同的方法制备维生素C泡腾片 ,从崩解度、溶解性 ,泡腾效果、外观等综合评价。结果 采用酸碱混合非水制粒法和粉末直接压片法制得的泡腾片各项评价指标均较好。结论 采用以上二法制得的维生素C泡腾片质量符合中国药典规定 ,具有一定的推广价值
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| 关 键 词： | 抗坏血酸 工艺学 制药 泡腾片 |
| 文章编号： | 1007-6611(2004)01-0022-03 |
| 修稿时间： | 2003年6月20日 |
Preparation of vitamin C effervescent tablets |
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| ZHANG Li-feng,SHI Xiu-jin,ZHANG Shu-qiu,et al.Preparation of vitamin C effervescent tablets[J].Journal of Shanxi Medical University,2004,35(1):22-24. |
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| Authors: | ZHANG Li-feng SHI Xiu-jin ZHANG Shu-qiu |
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| Abstract: | Objective To select formulation for vitamin C effervescent tablets. Method Four different methods were used to prepare vitamin C effervescent tablets. The formulations were evaluated by disintegration, dissolution, effervescent effect and appearance. Result The vitamin C effervescent tablets prepared by the methods of wet granulation and powder tablet presses were better. Conclusion The quality of vitamin C effervescent tablets prepared by both methods meets Chinese Pharmacopoeia(edition 2000) regulations. |
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| Keywords: | ascorbic acid technology pharmaceutical effervescent tablets |
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