肺炎支原体感染并发传染性单核细胞增多症5例临床分析

目的 :探讨小儿肺炎支原体 (MP)感染并发传染性单核细胞增多症 (传单 )的临床特征。方法 :对ELISA方法检测EB病毒 (EBV)、巨细胞病毒 (CMV)、疱疹病毒 (HHV)等IgM和PCR检测EBV -DNA均阴性 ,而MP -IgM和PCR检测MP -DNA均阳性的 5例传单患儿病历资料进行回顾性分析。结果 :5例均有发热、淋巴结肿大、咽峡炎、肝肿大 ,脾肿大 2例 ,咳嗽5例 ,鼻塞、眼睑浮肿 2例 ,腮腺肿大、皮疹 1例 ,肺部炎症、心肌损害 2例。 4例仅用阿奇霉素 ,1例仅用红霉素治疗 2周痊愈。结论 :MP感染可并发传染性单核细胞增多症 ,临床特征主要为不规则发热、淋巴结肿大、咽峡炎、肝脾肿大 ,阿奇霉素及红霉素治疗效果好。

A study on infectious mononucleosis with mycoplasma pneumoniae

Objective:To study the clinical features of infectious mononucleosis synsdrome due to mycoplasma pneumoniae in children.Methods:5 children with MP-IgM( ),PCR MP-DNA( ),EBV-IgM(-),CMV-IgM(-),HHV-IgM(-),EBV-DNA(-) were analyzed.All patients were diagnosed as infectious mononucleosis due to mycoplasma pneumoniae.Results:All the patients(100%) had fever,enlarged lymph nodes,angina and liver tumefaction.2 cases had spleen tumefaction;5 case had cough;2 cases had nasal obstruction and swollen blepharon;1 case had enlarged parotid gland and skin eruption,and 2 cases had pneumonia and myocarditis.4 cases were cured with azithromycin,and 1 case were cured with abomacetin for 2 weeks.Conclusion:Mycoplasma pneumoniae can lead to infectious mononucleosis syndrome.The main clinical features include irregular fever,angina,enlarged lymph nodes and hepatosplenomegaly.Azithromycin and abomacetin are effective for therapy.