Self-repair capability of surgically created incisions in TMJ disc: An experimental study on goats |
| |
| Institution: | 1. The State Key Laboratory of Oral Diseases and West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;2. Department of Cosmetic Surgery, The Third Hospital of Chengdu, Chengdu 610031, China;1. Dental Research Center, Tehran University of Medical Sciences, Ghods St., Enghelab Ave., P.O. Box: 14155-5583, 14174 Tehran, Iran;2. Department of Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Sciences, North Karegar St., Tehran, Iran;3. School of Dentistry, Tehran University of Medical Sciences, North Karegar St., Tehran, Iran;1. Department of Clinical Science, Faculty of Veterinary Medicine, Urmia University, Nazloo Road, Urmia 57153 1177, Iran;2. Department of Clinical Sciences, Faculty of Veterinary Medicine, Urmia Branch, Islamic Azad University, Salmas Road, Urmia 3737, Iran;3. Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4, Canada;1. Department of Otolaryngology, Shahid Beheshti Medical University, Loghman Hakim Hospital, Kargar St, Tehran, Iran;2. Department of Otolaryngology, Ahwaz University of Medical Sciences, Ahwaz, Iran;1. Department of Plastic, Reconstructive and Maxillo-Facial Surgery, and Burn Unity Hospital de São João, Porto Medical School, Alameda Professor Hernâni Monteiro, 4202-451 Porto, Portugal;2. CMUP – Center for Mathematics of University of Porto, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal;3. Spinal Neuronal Networks Group, IBMC – Instituto de Biologia Molecular e Celular, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal |
| |
| Abstract: | This study was to investigate whether surgically created incisions in discs at different sizes would heal spontaneously. Thirty mature goats were randomly divided into group A (1 mm), group B (3 mm) and group C (5 mm) according to the length of incision on the discs. Five animals in each group were sacrificed at 3 and 6 months postoperatively. The disc and condyle were evaluated by gross, histological and immunohistochemistry examinations. 1-mm discal incisions healed spontaneously with nearly normal gross and histological appearance at 6 months postoperatively, while 3-mm and 5-mm discal incisions failed to heal. Degenerative changes were observed in the fibrocartilage in both 3-mm and 5-mm incision groups, with a greater extent in the 5-mm group. Our results suggested that the TMJ disc of goat has limited self-repair capability to damage, which will be useful for making pre-surgical decisions related to the size and healing period of TMJ disc perforations. |
| |
| Keywords: | Temporomandibular joint Articular disc Goat Self-repair |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
