Management of locally aggressive mandibular tumours using a gas combination cryosurgery |
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Institution: | 2. Department of Neurosurgery, University of Pennsylvania Health System, 3 Silverstein Pavilion, 3400 Spruce Street, Philadelphia, PA 19104, USA;3. Department of Radiology, University of Pennsylvania Health System, 219 Dulles Building, 3400 Spruce Street, Philadelphia, PA 19104, USA |
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Abstract: | This study evaluated the results of curettage followed by cryosurgery using a combination of propane, butane, and isobutane gas for several benign but locally aggressive bone tumours on the mandible. Twenty-nine patients (16 men and 13 women) participated in the study. Patient ages ranged from 6 to 87 years (mean, 23.72 years). Before enucleation and cryosurgery, some patients received prior treatment consisting of marsupialisation to decrease tumour size. Twenty-seven of the 29 patients (93.10%) showed no evidence of clinical or radiographic recurrence after treatment through enucleation and cryosurgery. Wound dehiscence, which was observed in all cases, healed by second intention. The average follow-up period was 70.55 months (range, 53–120 months). These results suggest that enucleation followed by cryosurgery is an effective therapy for managing locally aggressive mandible tumours. In addition, this treatment is a less expensive intervention than more radical procedures. |
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Keywords: | Cryosurgery Cryotherapy Jaw neoplasms |
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