额叶功能评定量表在房颤患者中的应用及相关因素分析

目的 使用额叶功能评定量表(Frontal assessment battery,FAB)评估房颤患者执行功能,并进行相关因素分析,以探索FAB识别房颤相关认知障碍的有效性。方法 选取本院30例房颤患者为房颤组,选择同期29例健康人群为健康对照组,使用FAB评估其执行功能并进行比较,同时分析FAB与年龄、性别、学历、病程、房颤类型、CHA2DS2-VASc评分、HAS-BLED评分及简易智能精神状态检查量表(Mini-mental state examination,MMSE)评分的关系。结果 与健康对照组比较,房颤组FAB总得分明显降低,在概念化能力、动作程序性和对干扰的敏感度方面表现更差; Spearman相关分析显示FAB分数与房颤患者的学历、MMSE分数呈正相关,而与CHA2DS2-VASc评分、HAS-BLED评分呈负相关。结论 FAB有助于识别房颤患者执行功能受损。

The application of the frontal assessment battery in patients with atrial fibrillation

ObjectiveTo explore the effectiveness of frontal assessment battery(FAB)in identifying cognitive impairments associated with atrial fibrillation(AF).Methods 30 patients with AF and 29 healthy subjects were enrolled in this study. FAB was used to evaluate their executive function. The relationship between FAB and age, gender, education, course of the disease, atrial fibrillation type, CHA2DS2-VASc score, HAS-BLED score, and mini-mental state examination(MMSE)score was analyzed.Results Compared with the healthy control group, the total FAB score of AF patients was significantly decreased. The patients with AF performed worse in conceptualization, motor series, and sensitivity to interference. Spearman correlation analysis showed that the FAB score was positively correlated with the education and MMSE score of the patients with AF, while it was negatively correlated with the CHA2DS2-VASc score and the HAS-BLED score.Conclusion FAB is helpful to identify impaired executive function in patients with AF.