64层螺旋CT仿真内镜联合CT靶扫描对中央型小细胞肺癌支气管表征改变的诊断价值

目的探讨64层螺旋CT（MSCT）仿真内镜联合CT靶扫描在中央型小细胞肺癌（SCLC）诊断中的价值。方法采用回顾性研究方法，选取2018年1月~2021年2月在我院就诊的中央型SCLC患儿72例作为观察组，同时选取中央型良性病变患者70例作为对照组，分析两组MSCT仿真内镜、CT靶扫描图像。结果观察组CT靶扫描特征：毛刺征、胸膜凹陷征和空泡征比例分别为33.33%、75.00%和51.39%，高于对照组（P < 0.05）；观察组和对照组CT靶扫描特征中形态不规则、空气支气管征比例差异无统计学意义（P>0.05）；MSCT仿真内镜与纤维支气管镜结果一致性Kappa值为0.782（P < 0.05）；MSCT仿真内镜联合CT靶扫描诊断中央型SCLC的敏感度、准确性和阴性预测值明显高于CT靶扫描（P < 0.05）；MSCT仿真内镜联合CT靶扫描、CT靶扫描诊断中央型SCLC的特异性、阳性预测值比较差异无统计学意义（P>0.05）。结论MSCT仿真内镜联合CT靶扫描在中央型SCLC诊断中有较好的应用价值，值得临床使用。

Diagnostic observation of 64 slice spiral CT virtual endoscopy combined with CT target scan on bronchial characterization changes of central small cell lung cancer

ObjectiveTo investigate the value of 64 slice spiral CT (MSCT) virtual endoscopy combined with CT target scan in the diagnosis of central small cell lung cancer (SCLC).MethodsA total of 72 children with central SCLC in our hospital from January 2018 to February 2021 were selected as the observation group. Seventy patients with central benign lesions were selected as the control group. The MSCT virtual endoscopy and CT target scanning images were analyzed.ResultsThe age of observation group was significantly higher than that of control group (P < 0.05). The proportions of burr sign, pleural depression sign and vacuolar sign in the CT target scanning features of the observation group were significantly higher than those in the control group (P < 0.05). There was no significant difference between the observation group and the control group in the proportion of irregular morphology and air bronchial sign of the CT target scanning features (P>0.05). The consistent Kappa value of MSCT virtual endoscopy and fiberoptic bronchoscope was 0.782(P < 0.05). The sensitivity, accuracy and negative predictive values of MSCT virtual endoscopy combined with CT target scan in the diagnosis of central SCLC were significantly higher than those of CT target scan (P < 0.05). There was no significant difference in specificity and positive predictive value between MSCT virtual endoscopy combined with CT target scan and CT target scan in the diagnosis of central SCLC (P>0.05).ConclusionMSCT virtual endoscopy combined with CT target scan has a good application value in the diagnosis of central SCLC.