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胆总管热盐水灌注对犬胆管上皮及肝肾功能的影响
引用本文:曹智刚,白彬,郭启勇.胆总管热盐水灌注对犬胆管上皮及肝肾功能的影响[J].医学影像学杂志,2007,17(11):1217-1220.
作者姓名:曹智刚  白彬  郭启勇
作者单位:1. 哈尔滨医科大学附属第二医院放射科,黑龙江,哈尔滨,150086
2. 中国医科大学附属第二医院放射科,辽宁,沈阳,110001
摘    要:目的:观察胆总管灌注温热盐水对犬胆管和肝肾功能的影响。方法:8条犬DSA下穿刺胆囊胆总管内置入导管,42℃~43℃温热盐水灌注。术前及术后查肝肾功能,结果用单因素方差分析。处死动物,HE染色观察胆管病理变化。结果:灌注热疗后1周内,肝肾功能指标无显著变化(P>0.05)。光镜观察灌注局部胆管病理:3天可见淋巴细胞浸润,1周可见淋巴细胞增生,2周可见粘膜下腺体增生。未见粘膜上皮损伤。结论:经胆总管42℃~43℃温热盐水灌注15min,1周内对肝、肾功能无明显影响;2周内光镜观察未见胆管粘膜上皮损伤性改变。

关 键 词:胆管  肝肾功能    灌注  
文章编号:1006-9011(2007)11-1217-04
修稿时间:2007-05-22

The effects on canine bile duct tissue and hepatic and renal function in response to warm saline water perfusion in the common bile duct
CAO Zhi-gang,BAI Bin,GUO Qi-yong.The effects on canine bile duct tissue and hepatic and renal function in response to warm saline water perfusion in the common bile duct[J].Journal of Medical Imaging,2007,17(11):1217-1220.
Authors:CAO Zhi-gang  BAI Bin  GUO Qi-yong
Institution:1. Department of Radiology, the Second Affdiated Hospital of Haerbin Medical University, Haerbln 150086, P. R. China 2. Department of Radiology, the Second Affiliated Hospital of Chinese Medical University, Shenyang 110001, P. R. China
Abstract:
Keywords:Bile duct  Heptic and renal function  Hot  Perfusion  Dog
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