脑心通对急性心肌梗死患者御炎效果的观察与护理

目的：探讨脑心通对急性心肌梗死（AMI）患者的御炎效果及护理对策。方法：用脑心通治疗25例AMI患者3个月，于治疗前后检测患者血清白介素-18（LI-18）和肿瘤坏死因子-α（TNF-α）水平，并与常规治疗对照组比较。结果：治疗前脑心通治疗组血清LI-18、TNF-d均值与常规治疗组比较差别没有统计学意义（P〉0．05）；治疗后两组血清LI-18、TNF-α均值均较治疗前低（P〈0．01），此外脑心通治疗组治疗后血清LI-18、TNF—α均值低于常规治疗组（P〈0．01）。结论：急性心肌梗死患者存在明显的炎症反应，常规治疗后其致炎因素有所改善，用脑心通加常规治疗后其致炎因素改善程度较单纯常规治疗组好，在护理上，注意观察患者血清LI-18，TNF-α等致炎指标的变化情况，做到早期发现，早期治疗，在选用药物治疗时，应当努力保护其内皮功能，适当采用御炎等综合治疗措施，才能提高患者的远期疗效，降低复发率。

Observation and Nursing of Naoxintong on Effect of Inflammation Therapy for Patients with Acute Myocardial Infarction

Objective ： To explore the Naoxintong on the effect of inflammation therapy for the patients wih AMI and the nursing for it. Methods ： 25 patients with AMI have been treated with Naoxintong for three months, then determined the level of LI-18 and TNF-α in serum for the patients before and after treatment, and compare with the control group which be deal with regular treatment. Results ： Compare with regular treatment group, There is no statistical significant difference of the mean value of LI-18 and TNF-α in serum in Naoxintong treatment group before treatment（P〉0.05）, but they all decreased after treatment（P〈0.01）, furthermore, which in Naoxintong treatment group are all lower than regular treatment group（P〈0.01）. Conclusions ： There is significant inflammatory reaction in patients with AMI, It could be improved after regular treatment, and better improvement if adding Naoxintong. On the nursing work, it must observe the LI-18, TNF-α and other proinflammatory indices for the patients carefully , and earlier found, earlier treatment. All the chose medicine must has the function to protect its endothelial function, and using the inflammation cure and other combined treatment properly, and then it could increase the long-dated curative effect for the patient and decrease the recurrence rate.