裂叶荆芥芥穗的化学成分研究

 目的：对裂叶荆芥［Schizonepeta mulifida（L.）Briq.］芥穗的化学成分析进行研究。方法：利用溶剂提取和硅胶、聚酰胺、活性炭柱层析进行分离。结果：得到3个化合物，根据化合物的理化性质和光谱数据鉴定其结构。其中1个为已知成分即脱氢枞油烯（dehydrosylvestrene，V），另2个为新成分，分别命名为新壬四酸（neoenneaanetetraoic acid，Ⅶ）、3-亚胺基-N-氮代乙酰胺基丁内酰胺（3-imino-N-nitrogen substituted acetamidocyclic buty amide，Ⅷ）。结论：3个化合物均为首次从该植物中分得。另外还得到1个正高级烷烃混合物，经GC-MS分析证明内含十七种正碳烷。

Studies on the chemical constituents of the ear of Schizonepeta Mulifida

OBJECTIVE:To investigate the chemical constituents of the ear of Schizonepeta mulifida (L.)Briq. METHODS：Ingredients of the ear of this plant were separated by means of solvent extraction and chromatography on silica gel and polyamide and activated charcoal. RESULTS：Three components were isolated. Their structures were elucidated based on the spectral analysis. One of them is a known compound i.e. dehydrosylvestrene (V). The other two were new compound,named neoenneaanetetraoic acid (Ⅶ)，and 3-imino-N-nitrogen substituted acetamide cyclic buty amide (Ⅷ). CONCLUSION：These 3 compounds were isolated from the plant for the first time.By the way, a mixture of n-alkane was also obtained which contains seventeen n-alkane compounds proved by GC-MS.