| Abstract: | Sixty patients with pollenosis were examined: 36 city inhabitants and 24 villagers. The blood serum levels of IL-4, IFN-gamma and total IgE, production of IL-4, IFN-gamma by immunocompetent blood cells in vitro were determined. The correlation analysis detected more intensive involvement of IFN-gamma in allergic process in allergic patients living in the city. Estimation of spontaneous and induced cytokine production and their correlation (IS) showed that villagers had 2.5 times higher IS of IFN-gamma cytokine. |
