| 杭州市1995--2006年健康人群百日咳白喉破伤风抗体水平监测分析 |
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| 引用本文： | 黄利明,许二萍,杨洛贤,孟冬梅,朱冰,张小平,刘艳,王骏.杭州市1995--2006年健康人群百日咳白喉破伤风抗体水平监测分析[J].中国计划免疫,2009,15(1):68-71. |
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| 作者姓名： | 黄利明 许二萍 杨洛贤 孟冬梅 朱冰 张小平 刘艳 王骏 |
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| 作者单位： | 杭州市疾病预防控制中心,浙江,杭州,310006
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| 摘 要： | 目的了解杭州市健康人群百日咳、白喉、破伤风抗体水平。方法1995～2006年，在不同区（县、市），分2～4岁、6～8岁、13～15岁、25～39岁4个年龄组开展百日咳、白喉、破伤风抗体监测。结果百日咳抗体共监测1942人，保护率为93．87％，几何平均摘度为1：1037．36。其中农村2～4岁保护率低于其它三个年龄组，与6～8岁、13～15岁组保护率差异有非常显著的统计学意义（χ^2=8．80、6．13；P均〈0．01）。白喉抗体监测2141人，阳性率91．59％，几何平均浓度（GMC）为0．291国际单位／毫升（IU／m1）。破伤风抗体监测2141人，阳性率72．35％，GMC为0．095IU／ml。结论应加强农村地区的免疫规划管理及预防接种工作。
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| 关 键 词： | 百日咳抗体 白喉抗体 破伤风抗体 监测 |
Observation of Immunity Level of Pertussis-Diphtheria-Tetanus in Healthy People in Hangzhou City during 1995--2006 |
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| Institution: | HUANG Li-ming,XU Er-ping,YANG Luo-xian,etal. (HangzhouCity Center for Diseases Prevention and Control,Hangzhou 310006 Zhejiang, China) |
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| Abstract: | Objective To study the pertussis-diphtheria-tetanus immunity level of healthy people in Hangzhou. Methods Pertussis antibody, diphtheria antitoxin and tetanus antitoxin were tested. We carried out surveillance in different counties among the people at 2-- 4,6-- 8,13-- 15, 25--39 age group during 1995--2006. Results It showed that the pertussis antibody positive rate of 1942 persons was 93.87% ,GMT 1 ： 1037. 36 IU/ml,the antibody of people in countryside for the people at 2--4 age group was lower than that of other groups and the difference was significant compared with 6 -- 8,13 - 15 age group （χ^2 = 8.80,6.13, P 〈 0.01 ）. The diphtheria antitoxin positive rate of 2141 persons was 91.59%,with the GMT was 0. 2911IU/ml. The tetanus antitoxin positive rate of 2141 persons was 72.35% ,GMT 0. 095IU/ml. Conclusions We need to strengthen the EPI work in rural areas. |
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| Keywords: | Pertussis antibody Diphtheria antitoxin Tetanus antitoxin Surveillance |
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