| 幽门螺杆菌细胞毒素相关蛋白A与溃疡病的关系 |
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| 引用本文： | 方大鑫,虞则敏. 幽门螺杆菌细胞毒素相关蛋白A与溃疡病的关系[J]. 湘南学院学报(医学版), 2003, 5(1): 7-8 |
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| 作者姓名： | 方大鑫 虞则敏 |
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| 作者单位： | 苏州市平江区人民医院,江苏,苏州,215001 |
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| 摘 要： | 目的 探讨幽门螺杆菌 (Hp)细胞毒素相关蛋白A(CagA)与溃疡病的关系。方法 采用ELISA方法对 98例溃疡病患者进行血清CagA -Hp -IgG抗体检测 ,治疗后半年再次检测。结果 5 0例十二指肠球部溃疡 (DU)阳性率为10 0 % ,4 8例胃溃疡 (GU)阳性率为 83.3% ;半年后复检DU阳性率为 10 % ,GU阳性率为 7.5 % ,治疗前后两者阳性率具有显著性差别 (P <0 .0 1)。结论 CagA与溃疡病密切相关。
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| 关 键 词： | 幽门螺杆菌 细胞毒素相关蛋白A 溃疡病 |
| 文章编号： | 1671-4105(2003)01-0007-02 |
| 修稿时间： | 2002-10-14 |
Study on the Relation between CagA of Hp and Ulcerous Diseases |
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| Fang Daxin,Yu Zemin. Study on the Relation between CagA of Hp and Ulcerous Diseases[J]. JOurnal of Xiangnan University(Medical Sciences), 2003, 5(1): 7-8 |
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| Authors: | Fang Daxin Yu Zemin |
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| Abstract: | Objective To explore the relation between CagA of Hp and the ulcerous. Methods The CagA-Hp-IgG of serum from 98 cases with ulcerous diseases was determined by ELISA. After the treatment for half a year it was measured again by the same method. Results 100% positive reaction appeared in 50 cases with duodenum ulcers, and 83.3% positive reaction appeared in 48 cases with gastric ulcers; after the treatment lasted half a year, 10% positive reaction appeared in 50 cases with duodenum ulcers, and 7.5% positive reaction appeared in 48 cases with gastric ulcers. Conclusions The CagA of Hp and the ulcerous diseases have the close affinity. |
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| Keywords: | Helicolbacter pylori Ulcerous disceases CagA |
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