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涎腺腺癌细胞系对葫芦素BE的敏感性研究
引用本文:王莉娟,李龙江,杨凯,温玉明,王昌美.涎腺腺癌细胞系对葫芦素BE的敏感性研究[J].四川医学,2003,24(6):596-597.
作者姓名:王莉娟  李龙江  杨凯  温玉明  王昌美
作者单位:1. 四川大学华西医院,四川,成都,610041
2. 四川大学华西口腔医学院,四川,成都,610041
摘    要:目的 观察其有多种生物活性的葫芦素BE对涎腺腺癌细胞的杀伤作用。方法 用四唑盐显色法(MTT法)检测人腺样食性癌(ACC-M)和粘液表皮样癌(MEC-1)细胞系对葫芦素BE的敏感性实验。结果 葫芦素BE对两种腺癌细胞系均有较高的相对抗肿瘤活性(RAA值分别为345、148)。结论 实验结果为葫芦素BE治疗涎腺腺癌的进一步研究提供了重要依据。

关 键 词:葫芦素BE  涎腺肿瘤  腺癌  四唑盐显色法(MTT)
文章编号:1004-0501(2003)06-0596-02

Chemosensitivity study on adenocarcinoma cell lines of human salivary gland to cucurbitacin BE
Wang Li -juan ,Li Longjiang ,Yang Kai ,et al..Chemosensitivity study on adenocarcinoma cell lines of human salivary gland to cucurbitacin BE[J].Sichuan Medical Journal,2003,24(6):596-597.
Authors:Wang Li -juan  Li Longjiang  Yang Kai  
Institution:Wang Li -juan 1,Li Longjiang 2,Yang Kai 2,et al. 1 West China Hospital of Sichuan Univers it y,Sichuan Chengdu,610041,2.West Ch ina College of Stomatology,Sichuan Unive rsity,Sichuan Chengdu,610041
Abstract:Objective To observe the effects that Cucurbitacin BE with kinds of biological activities kil l the adenocarcinoma of salivary gland.Methods Chemosensitivity of h uman adenoid cystocarcinoma and mucoepid ermoid carcinoma cell lines to Cucurbita cin BE was tested with the MTT assay.Results Two kinds of cell lines had higher sensitivity to Cucurbitacin BE,Relative anti-tumor activities(RAA)we re 345 and 148,respectively.Conclu sion The results provide an import ant base to further study the treatment of using Cucurbitacin BE.
Keywords:cucurbitacin BE  neoplasms of salivary gland  adenocarcinom a  MMT assay
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