| 柴芩口服液的质量标准研究 |
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| 引用本文： | 高礼杰,王晓卫,蒋超,刘辉. 柴芩口服液的质量标准研究[J]. 中国药房, 2011, 0(7): 640-641 |
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| 作者姓名： | 高礼杰 王晓卫 蒋超 刘辉 |
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| 作者单位： | 湖北省中山医院药学部;广州军区武汉总医院药剂科; |
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| 摘 要： | 目的:建立柴芩口服液的质量标准。方法:采用薄层色谱(TLC)法对方中的黄芩、白芍、板蓝根进行定性鉴别;采用高效液相色谱法测定制剂中黄芩苷的含量。结果:TLC斑点清晰,分离度好;黄芩苷在49.2～492.0μg·mL-1范围内与峰面积积分值呈良好线性关系(r=0.9999),平均回收率为100.2%(RSD=0.59%,n=9)。结论:所建标准可用于柴芩口服液的质量控制。
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| 关 键 词： | 柴芩口服液 黄芩苷 薄层色谱法 高效液相色谱法 |
Study on Quality Standard of Chaiqin Oral Solution |
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| GAO Li-jie WANG Xiao-wei,JIANG Chao,LIU Hui. Study on Quality Standard of Chaiqin Oral Solution[J]. China Pharmacy, 2011, 0(7): 640-641 |
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| Authors: | GAO Li-jie WANG Xiao-wei JIANG Chao LIU Hui |
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| Affiliation: | GAO Li-jie(Dept. of Pharmacy,Hubei Zhongshan Hospital,Wuhan 430033,China) WANG Xiao-wei,JIANG Chao,LIU Hui(Dept. of Pharmacy,Wuhan General Hospital of Guangzhou Military Command,Wuhan 430070,China) |
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| Abstract: | OBJECTIVE： To establish quality standard of Chaiqin oral solution. METHODS： The Scutellaria baicalensis, Paeonia lactiflora and lsatis indigotica in Chaiqin oral solution were identified by TLC respectively. The content of baicalin in Chaiqin preparation was determined by HPLC. RESULTS： TLC spots were clear and well-separated. The linear range of baicalin was 49.2- 492.0μg·mL^-1（r=0.999 9） with an average recovery of 100.2% （RSD=0.59%, n=9）. CONCLUSION： The method is simple, practicable and sensitive for the quality control of Chaiqin oral solution. |
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| Keywords: | Chaiqin oral solution Baicalin TLC HPLC |
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