| 缬沙坦联合卡维地洛治疗慢性心力衰竭的临床研究 |
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| 引用本文： | 王会玖. 缬沙坦联合卡维地洛治疗慢性心力衰竭的临床研究[J]. 中国药房, 2011, 0(4): 348-350 |
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| 作者姓名： | 王会玖 |
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| 作者单位： | 河南安阳市人民医院心内科; |
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| 摘 要： | 目的:探讨缬沙坦联合卡维地洛对慢性充血性心力衰竭心功能及心室重塑的影响。方法:66例充血性心力衰竭患者随机分为观察组(缬沙坦联合卡维地洛)和对照组(常规治疗)。对照组给强心苷及利尿药常规治疗,观察组在常规治疗基础上加用缬沙坦及卡维地洛。疗程6个月。比较2组治疗前后心率、收缩压、6min步行试验、左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)及左心室射血分数(LVEF),并进行统计学分析。结果:对照组治疗后心率显著下降、6min步行试验、LVEF等指标均显著改善,与治疗前比较,差异有统计学意义(P<0.05);观察组治疗后心率、收缩压、LVEDD、LVESD均显著下降、6min步行试验及LVEF显著改善(P<0.05),与对照组比较,差异均有统计学意义(均P<0.05)。结论:缬沙坦联合卡维地洛改善慢性充血性心力衰竭心功能并逆转心室重塑。
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| 关 键 词： | 充血性心力衰竭 缬沙坦 卡维地洛 |
Clinical Study on Valsartan Combined with Carvedilol in the Treatment of Chronic Heart Failure |
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| WANG Hui-jiu. Clinical Study on Valsartan Combined with Carvedilol in the Treatment of Chronic Heart Failure[J]. China Pharmacy, 2011, 0(4): 348-350 |
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| Authors: | WANG Hui-jiu |
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| Affiliation: | WANG Hui-jiu(Dept.of Cardiology,Anyang Municipal People's Hospital of Henan Province,Anyang 455000,China) |
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| Abstract: | OBJECTIVE:To investigate the effects of valsartan combined with carvedilol on ventricular remodeling and function in patients with chronic congestive heart failure.METHODS:66 patients with chronic congestive heart failure were randomly divided into observation group and control group.Both group received conventional therapy,i.e.cardiac glycoside and diuretics.The observation group was additionally given valsartan and carvedilol for 6 months.heart rate,systolic pressure,six-minute walking test as well as lef... |
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| Keywords: | Congestive heart failure Valsartan Carvedilol |
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