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Brain Region Specific Actions of Regulator of G Protein Signaling 4 Oppose Morphine Reward and Dependence but Promote Analgesia
Authors:Ming-Hi Han  Robert H Ring  Kassi Psifogeorgou  Shari Birnbaum  Rachael Neve  Venetia Zachariou
Institution:a Department of Psychiatry, UT Southwestern Medical Center, Dallas, Texas
b Department of Pharmacology, University of Crete, Faculty of Medicine, Heraklion, Crete, Greece
c Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts
d Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, New York
e Discovery Neuroscience, Wyeth Research, Princeton New Jersey
Abstract:
Keywords:AAV-Cre  analgesia  fentanyl  HSV-RGS4  locus coeruleus  morphine  nucleus accumbens  place preference  tolerance  withdrawal
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