镇静/镇痛药对肝叶切除患者全身麻醉恢复期镇静程度的影响

目的:探讨镇静/镇痛药对肝叶切除患者全身麻醉恢复期镇静程度的影响。方法:回顾我院择期行肝叶切除术肝功能正常全麻患者72例,年龄(58.39±9.54)岁,体重(58.51±8.53)kg,美国麻醉师协会(ASA)分级Ⅰ～Ⅱ级。根据Riker镇静-躁动分级分成3组,即躁动组(Riker5～7级)、平静合作组(Riker4级)、嗜睡组(Riker3级)。对比3组镇静/镇痛药用量。结果:躁动组13例,平静合作组45例,嗜睡组14例。3组一般情况、麻醉时间、总液体入量、术中血流动力学波动及维库溴铵的用量差异均无统计学意义(P>0.05)。嗜睡组咪达唑仑及舒芬太尼用量明显多于躁动组(P<0.05)。结论:嗜睡者的镇静/镇痛药用量明显多于躁动者。

Influence of Sedative and Analgesic Drugs on Sedative Situation in Patients with Partial Hepatectomy during Post-anesthesia Recovery Period

OBJECTIVE： To analyze the influence of sedative and analgesic drugs on sedative situation in patients with partial hepatectomy during post-anesthesia recovery period. METHODS： 72 patients undergoing selective partial hepatectomy （ASA Ⅰ - Ⅱ grade）, aged （58.39 ± 9.54） years and body weight of （58.51 ± 8.53） kg, were reviewed. Patients were divided into 3 groups according to Riker sedation-restlessness grade, i.e. restlessness group （Riker 5-7 grade）, sedation group （Riker 4 grade） and somnolence group （Riker 3 grade）. The dosage of sedation and analgesic drugs was compared among 3 groups. RESULTS： There were 13 cases in restlessness group, 45 cases in sedation group and 14 cases in somnolence group. There was no significant difference in the differences of general situation, analgesia time, total amount of liquid, intraoperative hemodynamic change and the dose of vecuronium bromide （P〉0.05）. The dose of midazolam and sufentanil in somnolence group were significantly higher than restlessness group （P〈0.05）. CONCLUSION： The dose of sedative and analgesic drugs in somnolence group is significantly higher than in restlessness group.