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老年慢性阻塞性肺疾病的病原菌构成及耐药性分析
引用本文:陈康中,陈德钏,兰德权.老年慢性阻塞性肺疾病的病原菌构成及耐药性分析[J].中国药房,2011(18):1681-1682.
作者姓名:陈康中  陈德钏  兰德权
作者单位:浙江苍南县第三人民医院呼吸科;
摘    要:目的:分析老年慢性阻塞性肺疾病(COPD)的病原菌构成及耐药性,为临床合理选用抗菌药物提供参考。方法:对156例COPD患者的痰培养和药敏试验结果进行回顾性分析。结果:革兰阴性(G-)菌125株,以铜绿假单胞菌为首;革兰阳性(G+)菌48株,以金黄色葡萄球菌为首;真菌18株。铜绿假单胞菌对氨苄西林/舒巴坦、头孢哌酮/他唑巴坦、亚胺培南和头孢他啶的耐药率均<35%;肺炎克雷伯菌和大肠埃希菌对氨苄西林/舒巴坦、头孢哌酮/他唑巴坦和亚胺培南耐药率均<35%;鲍曼不动杆菌除了对亚胺培南和头孢哌酮/他唑巴坦敏感外,对其他药物的耐药率均>60%。G+菌耐药性严重,但对万古霉素和替考拉宁敏感率均为100.0%。结论:老年COPD患者的主要病原菌为G-菌,呈现出多重耐药性,耐药率也不断增加。

关 键 词:慢性阻塞性肺疾病  病原菌  药敏试验  耐药性

Analysis of Drug Resistance and Etiology Composition of Senile COPD
CHEN Kang-zhong,CHEN De-chuan,LAN De-quan.Analysis of Drug Resistance and Etiology Composition of Senile COPD[J].China Pharmacy,2011(18):1681-1682.
Authors:CHEN Kang-zhong  CHEN De-chuan  LAN De-quan
Institution:CHEN Kang-zhong,CHEN De-chuan,LAN De-quan(Dept.of Respiratory Disease,Cangnan County Third People's Hospital of Zhejiang Province,Cangnan 325800,China)
Abstract:OBJECTIVE:To analyze the etiology composition and drug resistance of senile COPD,and to provide reference for rational use of drugs in the clinic.METHODS:The results of sputum cultures and drug sensitive test in 156 senile COPD patients were analyzed retrospectively.RESULTS:There were 125 strains of Gram-negative bacteria,the most of them were Pseudomonas aeruginosas.There were 48 strains of Gram-positive bacteria,the most of them were Staphylococcus aureus,and there were 18 strains of fungus.The drug resis...
Keywords:COPD  Pathogenic bacteria  Drug sensitive test  Drug resistance  
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