老年脑梗死后痴呆危险因素的临床研究

目的：对老年脑梗死后痴呆的危险因素进行分析研究。方法：收集2009年1月到2011年1月在本院住院的180例老年脑梗死患者的临床资料进行统计分析，所有患者均行颈动脉彩超及头颅CT／MRI检查，用MMSE量表进行智能评定，先对研究资料进行单因素分析，然后再进行多因素非条件Logistic回归模型分析。结果：本组脑梗死后痴呆的发生率为28．9％（52／160）。统计学分析显示，患者年龄、文化程度的高低对脑梗死后痴呆存在一定程度的影响，高血压及既往脑血管病病史为脑梗死后痴呆的相关危险因素，颈动脉狭窄、多发性梗死、优势侧半球梗死、双侧半球及大面积梗死与脑梗死后痴呆的发生相关（P〈0．05）。结论：老年脑梗死后痴呆由多种因素引起，应对引起痴呆的危险因素进行积极干预。

The clinical study on the risk factors of dementia after brain infarction in old people

Objective： To investigate the risk factors of dementia after brain infarction in old people. Methods： Between January 2009 and January 2011,180 brain infarction old patients hospitalized in our hospital were collected for statistic analysis and performed carotid color duplex ultrasonography and cranial CT / MRI examination. Intelligent assessment was performed by MMSE scale. At first, single factor analysis was done in the research data. Thereafter, multivariate non-conditional Logistic regression analysis was then performed. Results： Of all patients ,the occurrence rate of cerebral infarction was 28.9%. The statistical analysis showed the certain impacts of age, education degree on dementia after brain infarction in old patients. The hypertension and the history of eerebrovascular disease were the risk factors of dementia. Carotid stenosis, multiple obstruction, dominant hemisphere infarction, bilateral hemispheres and a large area of infarction were correlated with the occurrence of dementia after cerebral infarction （ P 〈 0.05 ）. Conclusion： The dementia after cerebral infarction was caused by a variety of factors in old people. Thus, we should actively intervene he risk factors that cause the dementia.