EFFECTS OF INHALATION ANAESTHETIC AGENTS ON THE ELECTRICAL AND MECHANICAL ACTIVITY OF THE RAT DUODENUM |
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| Authors: | WRIGHT, J. W. HEALY, T. E. J. BALFOUR, T. W. HARDCASTLE, J. D. |
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| Affiliation: | Department of Surgery, Floor E, University Hospital, Queens Medical Centre Nottingham
University Hospital of South Manchester Withington, Manchester M20 8LR |
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| Abstract: | Sleep doses of halothane (4%), enflurane (2%) and diethyl ether(10%) were administered to fasting rats. Duodenal mechanicaland electrical activities were recorded using miniature extraluminalstrain gauges and silver/silver chloride bipolar electrodes.Halothane abolished, or significantly reduced, phase HI activityof the migrating myo-electnc complex whereas enflurane abolishedphase II activity but failed to reduce phase HI. Ether was associatedwith periods of intense activity throughout anaesthesia andthis activity persisted after recovery of consciousness. Allanaesthetic agents caused a marked slowing of the basic electricalrhythm. |
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