| 原儿茶醛对大鼠微循环影响的实验研究 |
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| 引用本文： | 沈玲红,王彬尧,王长谦,姚中一,俞国瑞. 原儿茶醛对大鼠微循环影响的实验研究[J]. 微循环学杂志, 2002, 12(2): 12-14 |
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| 作者姓名： | 沈玲红 王彬尧 王长谦 姚中一 俞国瑞 |
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| 作者单位： | 1. 上海第二医科大学附属仁济医院心内科,上海,200001
2. 上海本草生物医学工程研究所 |
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| 基金项目： | 上海本草生物医学工程研究所提供资金 |
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| 摘 要： | 目的 :探讨原儿茶醛对大鼠微循环的影响。方法 :采用静脉注射高分子量右旋糖酐造成大鼠微循环障碍模型 ,通过激光多普勒血流仪测量原儿茶醛对大鼠区域微循环灌流量的影响 ,同时在高倍显微镜下观察血细胞的形态变化。结果 :原儿茶醛能够显著增加微循环障碍大鼠微循环灌流量 ,同时伴随血细胞形态的改善。结论 :原儿茶醛有一定程度改善大鼠微循环障碍的能力
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| 关 键 词： | 原儿茶醛 微循环 激光多普勒血流仪 大鼠 |
| 修稿时间： | 2001-12-07 |
Experimental Study of Protocatechualdehyde for Microcirculation of Rats |
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| Shen Linghong,Wang Binyao,Wang Changqian,et al/Shanghai Renji Hospital,Shanghai. Experimental Study of Protocatechualdehyde for Microcirculation of Rats[J]. Chinese Journal of Microcirculation, 2002, 12(2): 12-14 |
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| Authors: | Shen Linghong Wang Binyao Wang Changqian et al/Shanghai Renji Hospital Shanghai |
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| Affiliation: | Shen Linghong,Wang Binyao,Wang Changqian,et al/Shanghai Renji Hospital,Shanghai 200001 |
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| Abstract: | To investigate the effect of Protocatechualdehyde on rats′ microcirculation.Method: A microcirculation disturbance rats models was builted b y i ntravenous injection of 10% high molecular weight dextran,detected the local mic rocirculation flow of rats by laser Doppler flowmeter and observed the morpholog ical change of blood cell under microscope at the same time.Results: Protocatechuldehyde can raise the flow of microcirculat ion of rats with the improvement of the shape of blood cell.Conclusion: Protocatechualdehyde could lessen the disturbance of microcirculation in rats. |
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| Keywords: | Protocatechualdehyde Microcirculation Laser Doppler flowmeter Rat |
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