| 生脉注射液减轻兔肾缺血再灌流损伤的作用研究 |
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| 引用本文： | 李莉华,邬丽莎,张春来,赵春玲,冉兵,盘强文,冯志强.生脉注射液减轻兔肾缺血再灌流损伤的作用研究[J].四川生理科学杂志,1997(2). |
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| 作者姓名： | 李莉华 邬丽莎 张春来 赵春玲 冉兵 盘强文 冯志强 |
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| 作者单位： | 泸州医学院生理教研室 646000
(李莉华，邬丽莎，张春来，赵春玲，冉兵，盘强文)，泸州医学院生理教研室 646000(冯志强) |
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| 摘 要： | 用自制的肾缺血再灌流损伤模型,在20只新西兰兔,研究了生脉注射液在肾缺血再灌流操作中的作用。结果表明:肾缺血再灌流24小时后,单纯缺血再灌流组动物血尿素氮和肌酐较缺血前显著升高;生脉防治组血尿素氮较缺血前显著升高,但肌酐无显著变化;在再灌流2小时和24小时,血中过氧化脂质(LPO)的含量,单纯缺血再灌流组较缺血前呈升高趋势,生脉防治组呈降低趋势,但差异均无显著性;再灌流24小时肾组织中LPO含量,生脉防治组较单纯缺血再灌流组肾脏呈严重坏死改变,生脉防治组仅有轻度变性。结果揭示:生脉注射液具有减轻兔肾缺血再灌流损伤的作用。
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| 关 键 词： | 肾缺血再灌流 生脉 过氧化脂质 肾功 |
THE EFFECTS OF SHENGMAI ON RELIEF OF RENAL INJURY BY ISCHEMIA - REPERFUSION IN RABBITS |
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| Li Lihua.Wu Lisha,Zhang Chunlai,Zhao Chunling,Ran Bing,Pan Qiangwen,Feng Zhiqiang
Dept. of Pharmacology,Luzhou Medical College Luzhou,Sichan.THE EFFECTS OF SHENGMAI ON RELIEF OF RENAL INJURY BY ISCHEMIA - REPERFUSION IN RABBITS[J].Sichuan Journal of Physiological Sciences,1997(2). |
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| Authors: | Li LihuaWu Lisha Zhang Chunlai Zhao Chunling Ran Bing Pan Qiangwen Feng Zhiqiang
Dept of Pharmacology Luzhou Medical College Luzhou Sichan |
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| Institution: | Li Lihua.Wu Lisha,Zhang Chunlai,Zhao Chunling,Ran Bing,Pan Qiangwen,Feng Zhiqiang
Dept. of Pharmacology,Luzhou Medical College Luzhou,Sichan 646000) |
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| Abstract: | |
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| Keywords: | renal ischemia - reperfusion Shengmai Lipid peroxides renal function |
| 本文献已被 CNKI 等数据库收录！ |
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