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99mTc-MIBI显像与99mTc-MDP骨显像诊断转移性骨肿瘤的对比研究
引用本文:张红,叶宏勋,苏成海.99mTc-MIBI显像与99mTc-MDP骨显像诊断转移性骨肿瘤的对比研究[J].华北煤炭医学院学报,2011,13(2).
作者姓名:张红  叶宏勋  苏成海
作者单位:1. 苏州大学附属第一医院,江苏苏州,215006
2. 泰兴市人民医院核医学科
摘    要:①目的 探讨99mTc-MIBI显像与99mTc-MDP骨显像在转移性骨肿瘤诊断价值上的差异.②方法 对68例经病理证实为恶性肿瘤并怀疑有骨转移的患者均进行99mTc-MIBI显像与99mTc-MDP全身骨显像(两项检查时间不超过1周),对比分析两种显像结果.③结果 68例患者中经临床证实骨转移32例,则99mTc-MIBI显像诊断转移性骨肿瘤总的灵敏度为80.2%,特异性为85.0%,准确性为82.4%;99mTc-MDP骨显像诊断转移性骨肿瘤总的灵敏度为70.8%,特异性为63.3%,准确性为67.6%.对于原发灶为乳腺癌、多发性骨髓瘤的患者所发生的骨转移,99mTc-MIBI显像比99mTc-MDP骨显像有优势;而对于原发灶为前列腺癌的患者所发生的骨转移,99mTc-MIBI显像探测能力则不及99mTc-MDP骨显像.④结论 99mTc-MIBI显像在评价肿瘤骨转移方面比传统的骨显像具有更好的敏感性、特异性和准确性.

关 键 词:99mTc-MIBI显像  99mTc-MDP骨显像  转移性骨肿瘤  骨髓转移  骨转移

The comparative study of 99mTc-MIBI and 99mTc-MDP bone imaging in detecting bone metastases
ZHANG Hong,YE Hongxun,SU Chenghai.The comparative study of 99mTc-MIBI and 99mTc-MDP bone imaging in detecting bone metastases[J].Journal of North China Coal Medical College,2011,13(2).
Authors:ZHANG Hong  YE Hongxun  SU Chenghai
Institution:ZHANG Hong,YE Hongxun,SU Chenghai(The First Affiliated Hospital of Soochow University,Jiangsu Soochow 215006,China)
Abstract:Objective To discuss diagnostic value of 99mTc-MIBI and 99mTc-MDP in imaging metastatic bone tumors.Methods 99mTc-MIBI and 99mTc-MDP bone imaging were performed on 68 patients with proven malignant lesions and suspected bone metastases(Two exams were maken during one week),then the results from 99mTc-MIBI and 99mTc-MDP bone imaging were compared.Bone metastases were confirmed by tissue biopsy.Results Bone metastases were confirmed clinically in 32 of 68 patients.The sensitivity,specificity and accuracy of 9...
Keywords:Metastatic bone tumors  Bone marrow metastases  Bone metastases  99mTc-MIBI imaging  99mTc-MDP bone imaging  
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