红霉素肠溶微丸制备工艺 |
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引用本文: | 刘海.红霉素肠溶微丸制备工艺[J].中国医药工业杂志,2003,34(2):84-86. |
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作者姓名: | 刘海 |
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作者单位: | 深圳万和制药有限公司,广东深圳,518055 |
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摘 要: | 采用挤出—滚圆技术制备红霉素微丸丸芯,并用正交设计筛选其制备工艺;以甲基丙烯酸共聚物水分散体为包衣材料,建立微丸包衣数学模型指导包衣工艺。
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关 键 词: | 红霉素 肠溶微丸 制备 工艺 微丸包衣数学模型 |
文章编号: | 1001-8255(2003)02-0084-03 |
修稿时间: | 2002年6月20日 |
Preparation of Erythromycin Enteric Pellets |
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Authors: | LIU Hai |
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Abstract: | Erythromycin pellets were prepared by extrusion-spheronization technology, and the parameters were optimized by orthogonal design. Eudragit L30 D-55 was used as enteric coating material. A mathematical model was proposed to guide the coating technology. |
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Keywords: | erythromycin enteric pellets Eudragit L30 D-55 coating mathematical model |
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