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难治性癫痫的原因及药物治疗策略
引用本文:陈光辉. 难治性癫痫的原因及药物治疗策略[J]. 东南国防医药, 2003, 5(6): 469-474
作者姓名:陈光辉
作者单位:解放军南京总医院神经内科,南京,210002
摘    要:本文阐述了难治性癫痫的病因及预告因素 ,提出针对真性难治的药物治疗策略。新诊断癫痫的患者应首选单药治疗 ;当单药或 2种药治疗无效时应重新评估诊断 ,排除非痫性事件 ,权衡手术的利弊 ,并选择合理的多药治疗。

关 键 词:难治性癫痫  药物治疗
文章编号:1672-271X(2003)06-0469-06
修稿时间:2003-08-25

The underlying cause of medically refractory epilepsy and management strategy
CHEN Guang hui. The underlying cause of medically refractory epilepsy and management strategy[J]. Journal of Southeast China National Defence Medical Science, 2003, 5(6): 469-474
Authors:CHEN Guang hui
Affiliation:CHEN Guang hui. Department of Neurology,Nanjing General Hospital of PLA,Nanjing 210002,China
Abstract:The fundamental pathology of medically refractory epilepsy and major prognostic fctors are reviewed.This article focuses on the practical approaches to the management of refractory seizures.Monotherapy remains the treatment method of Choice for new onset epilepsy,but if seizures are coly partially controlled at maximally tolerated doses,consder rational polypharmacy.If two medications do not completely control scizures,the diagnosis should be reconsidered,surgical options,or using more than two drugs also be considered.
Keywords:Medically refractory epilepsy Antiepileptic drugs
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