FPIA法与RP-HPLC法检测肾移植患者环孢素血药浓度的比较研究 |
| |
引用本文: | 梁爽,张宁,吕慧怡,邓卅. FPIA法与RP-HPLC法检测肾移植患者环孢素血药浓度的比较研究[J]. 实用药物与临床, 2009, 12(5): 336-338 |
| |
作者姓名: | 梁爽 张宁 吕慧怡 邓卅 |
| |
作者单位: | 大连医科大学附属第二医院药剂科,大连,116027;大连医科大学药学院,大连,116027 |
| |
摘 要: | 目的比较反相高效液相色谱法(RP-HPLC)法与荧光偏振免疫(FPIA)法检测肾移植患者环孢素血药浓度结果,评价二者的相关性。方法分别采用RP-HPLC和FPIA方法测定20份血样,并对结果进行统计学处理。结果两种测定方法所得结果差异无统计学意义(P>0.05)。结论RP-HPLC和FPIA方法应用于肾移植患者环孢素血药浓度监测真实可信。
|
关 键 词: | 荧光偏振免疫法 高效液相色谱法 环孢素 血药浓度 |
Determination of CsA blood concentration in renal transplantation patients by FPIA and HPLC |
| |
Abstract: | Objective To compare the effects of FPIA and RP-HPLC methods in the determination of CsA blood concentration in renal transplantation patients,and to evaluate the correlation of them.Methods 20 different concentrations of clinical samples were determined by RP-HPLC and FPIA respectively.Results There was no difference in determination results of CsA between FPIA and RP-HPLC.Conclusion FPIA and RP-HPLC methods applied on the CsA blood concentration of patients undergoing renal transplantation are true and believable. |
| |
Keywords: | FPIA RP-HPLC CsA Blood concentration |
本文献已被 维普 万方数据 等数据库收录! |
|