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涎腺恶性淋巴上皮病损的免疫组化研究
引用本文:吴兰雁,周志瑜.涎腺恶性淋巴上皮病损的免疫组化研究[J].口腔颌面外科杂志,1996,6(3):188-191.
作者姓名:吴兰雁  周志瑜
作者单位:西医科大学口腔医院病理科,西医大附一院病理科
摘    要:涎腺恶性淋巴上皮病损(MLEL)是涎腺罕见的恶性肿瘤之一,具有明显的种族特性,好发于南部中国人。本文对12例MLEL(其中10例有随访资料)进行Keratin,S-100,GFAP,CEA免疫组化染色。结果发现Keratin免疫组化染色反应强者预后好,染色反应弱者预后差。以上四种抗体免疫组化染色结果尚提示MLEL的癌细胞具有与正常腺上皮细胞、肌上皮细胞及鳞状上皮细胞相似的抗原特性,提示该瘤来自涎腺导管上皮,常有鳞状上皮化生

关 键 词:涎腺  恶性淋巴上皮病损  免疫组化

AN IMMUNOHISTOCHEMICAL STUDY ON MALIGNANT LYMPHOEPITHEL LESION OF THE SALIVARY GLANDS
Wu Lan-yan,Zhou zhi-yu,Bu Hong et al.AN IMMUNOHISTOCHEMICAL STUDY ON MALIGNANT LYMPHOEPITHEL LESION OF THE SALIVARY GLANDS[J].Chinese Journal of Oral and Maxillofacial Surgery,1996,6(3):188-191.
Authors:Wu Lan-yan  Zhou zhi-yu  Bu Hong
Institution:College of stomatogy;West china University of Medical Sciences
Abstract:alignant lymphoepithelial lesions(MLEL) of the salivary glands are rare but occur more often in Southern chinese.The immunohistochemical staining of Keratin,S-100,GFAP,CEA were used in l2 cases of MLEL(10 of which have fol low-up imformation).The carcinoma showed an obvious adenoid,myoepithelial and epidermoid nature by immunohistochemicalstaining.The results suggested the origin of the tumor is ductul epithelium with squamous metaplasia and keratin immunostaining is useful in judging prognosis of the tumor.
Keywords:Salivary gland  Malignant lymphoepithelial lesion Immunohistochemistry
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