晚发性维生素K缺乏致颅内出血患儿136例分析

目的:提高对晚发性维生素K缺乏致颅内出血的认识,力争早期诊断、早期治疗、早期预防。方法:回顾性分析136例晚发性维生素K缺乏致颅内出血患儿的临床特点、病因及预后。结果:本组患儿136例中治愈84例(占61.76%),死亡11例(占8.08%),致残32例(占23.52%),对一些危重病人,外科手术治疗效果较好。结论:早期的诊断和治疗对降低病死率和致残率有重要意义,但预防同样关键,有效的预防措施为常规给新生儿、纯母乳喂养婴儿、有感染性疾病、腹泻病、肝胆疾病等的小婴儿定期补充VITK1。

Analysis of 136 Cases of Late Form of Vitamin K Deficiency Bleeding and Intracranial Haemorrhage in Infancy

Objective: To eveluate the cognition of intracranial haemorrhage associated with late vitamin K deficiency for early diagnosis,early treatment and early preservation.Method: A retrospective study was carried out as to the clinical features,etiopathogenisis and prognosis of intracranial haemorrhages by vitamin K deficiency in 136 infants.Result:84 cases(61.76 %) were healed,11 cases(8.08%)dead,32 cases(23.52%) with nervous system sequelaes,surgical intervention would be better for some severe patient.Conclusion: The early diagnosis and proper treatment of delayed vitamin K deficiency are of much clinical significance in reducing mortality rate and mutilation.Preservation were important,it could be prevented by periodical administration of supplementary vitamin K1 to newborn infant,infant with exclusively breast-fed,patient with infections,diarrhea,liver and gall disease.