| 健康人IgA特异性激活补体类循环免疫复合物的研究 |
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| 引用本文： | 彭宣宪 万雅各. 健康人IgA特异性激活补体类循环免疫复合物的研究[J]. 中国免疫学杂志, 1993, 9(3): 170-172 |
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| 作者姓名： | 彭宣宪 万雅各 |
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| 作者单位： | 南昌大学生物科学工程系微生物学教研室，南昌大学医院，南昌大学生物科学工程系微生物学教研室，南昌大学生物科学工程系微生物学教研室，江西省中心血站，江西省妇产医院 南昌330047，南昌330047，南昌330047 |
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| 基金项目： | 江西省自然科学基金资助课题 |
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| 摘 要： | 本文建立了检测IgA 特异性激活补体类循环免疫复合物(IgA/C3-CIC)的捕捉法ELISA,用于检测404例健康人血清标本,发现除脐血外的各个体均存在这类免疫复合物。其含量与年龄和性别有关,而与ABO 血型无明显关系。这与健康人血清IgA 水平的年龄和性别差异相似。提示健康人IgA/C_3—CIC的含量变化主要取决于血清IgA 水平,确定其正常值时应考虑到这些因素。同时也说明,对健康人这类免疫复合物的检测可以反映正常免疫反应的若干特点。
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| 关 键 词： | 免疫复合物 免疫球蛋白A 补体 |
CIRCULATING SPECIFIC IgA IMMUNE COMPLEXES ACTIVATING COMPLEMENT IN HEALTHY PERSONS |
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| Peng Xuanxian,et al. CIRCULATING SPECIFIC IgA IMMUNE COMPLEXES ACTIVATING COMPLEMENT IN HEALTHY PERSONS[J]. Chinese Journal of Immunology, 1993, 9(3): 170-172 |
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| Authors: | Peng Xuanxian et al |
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| Abstract: | plexes activating complement of 404 cases of healthy persons.It was found that there were thisimmune complexes in every case except umbilical blood,the amount of this immune complexeswere related to age and sex,but not to ABO blood types,which was similar to the relationshipbetween serum IgA and age and sex.These results suggests that the amount of circulating spe-cific IgA immune complexes activating complement in healthy persons depend chiefly on the levelof serum IgA,detecting this immune complexes may approach some characterizations on normalimmune response,and age and sex should be considered when normal value of the specific im-mune complexes is determined |
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| Keywords: | Circulating immune complexes Immunoglobulin A Complement Immune response Normal value |
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