| 胶质细胞源性神经营养因子在成年大鼠三叉神经节及三叉神经核团中的分布 |
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| 引用本文： | 冯士生,周长满,鄂玲玲,杨松. 胶质细胞源性神经营养因子在成年大鼠三叉神经节及三叉神经核团中的分布[J]. 解剖学报, 2004, 35(1): 26-29 |
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| 作者姓名： | 冯士生 周长满 鄂玲玲 杨松 |
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| 作者单位： | 北京军医学院解剖学教研室,北京,100071;北京军医学院解剖学教研室,北京,100071;北京军医学院解剖学教研室,北京,100071;北京军医学院解剖学教研室,北京,100071 |
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| 基金项目： | 全军医学科研基金面上项目 ( 98M117) |
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| 摘 要： | 目的 观察胶质细胞源性神经营养因子(GDNF)在成年大鼠三叉神经节及三叉神经核团内的分布，探讨其对三叉神经感觉神经元及运动神经元的作用。方法 抗GDNF多克隆抗体免疫组织化学ABC法。结果 成年大鼠三叉神经运动核、三叉神经感觉核簇及三叉神经节中出现GDNF免疫反应阳性。结论 成年大鼠三叉神经运动核、三叉神经感觉核簇及三叉神经节中存在GDNF神经元。
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| 关 键 词： | 胶质细胞源性神经营养因子 三叉神经运动核 三叉神经感觉核簇 三叉神经节 免疫组织化学 大鼠 |
THE DISTRIBUTION OF GDNF IN THE TRIGEMINAL NUCLEUS AND GANGLION OF ADULT RAT |
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| FENG Shi-sheng,ZHOU Chang-man ,E Ling-ling YANG Song. THE DISTRIBUTION OF GDNF IN THE TRIGEMINAL NUCLEUS AND GANGLION OF ADULT RAT[J]. Acta Anatomica Sinica, 2004, 35(1): 26-29 |
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| Authors: | FENG Shi-sheng ZHOU Chang-man E Ling-ling YANG Song |
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| Affiliation: | FENG Shi-sheng,ZHOU Chang-man *,E Ling-ling YANG Song |
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| Abstract: | Objective Investigate the effects of glial cell line-derived neurotrophic factor(GDNF) on trigeminal sensory and motor neurons. Methods The localization of GDNF in the neurons of trigeminal nucleus and ganglion of adult rat was studies by using anti-GDNF immunohistochemical staining technique. Results The positve GDNF immunoreactivity was present in the trigeminal motor neurons as well as the sensory neurons of trigeminal ganglion and trigeminal sensory nuclear complex.Conclusion These results indicate that GDNF neurons are present in the trigeminal ganglion as well as the trigeminal motor nucleus and sensory nuclear complex of adult rat. |
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| Keywords: | Glial cell line-derived neurotrophic factor(GDNF) Trigeminal motor nucleus Trigeminal sensory nuclear complex Trigeminal ganglion Immunohistochemistry Rat |
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