急性肺损伤与急性呼吸窘迫综合征临床研究进展

急性肺损伤(ALI)与急性呼吸窘迫综合征(ARDS)是临床常见的危重症,通常由严重感染、创伤、休克等许多直接或间接造成肺损伤的因素诱发。ALI/ARDS的病死率较高,肺组织损伤严重,氧合指数(PaO2/FiO2)水平高低是其诊断与病情判断的基本标准之一。ALI/ARDS目前没有特效治疗手段,主要的治疗措施是支持治疗,避免并发症的发生;限制性液体使用、低潮气量通气以及使用最小FiO2-PEEP可能对ALI/ARDS治疗有利。

Clinical Progress of Acute Lung Injury and Acute Respiratory Distress Syndrome

Acute respiratory distress syndrome and acute lung injury are well defined and readily recognised clinical disorders which commonly induced by severe infection, trauma and shock directly and indirectly. Mortality rates of acute lung injury is greatly high, and the tissues of lung injury is very severe. Oxygenation index （ Partial arterial pressure of oxygen [ PaO2 ]/fractional concentration of oxygen in inspired air[FiO2 ] ） is one of the basic criteria to diagnose and judge the state of illness.. ALI/ARDS has no specific treatment, The main treatment is supportive care,including avoiding complications, fluid management,reducing, tidal volume coupled with use of the minimum FiO2 -PEEP combination, which maybe helpful to this disorder.