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IgG4相关性淋巴结病的临床病理特点
引用本文:张卉,冯瑞娥. IgG4相关性淋巴结病的临床病理特点[J]. 国际病理科学与临床杂志, 2012, 32(4): 347-351
作者姓名:张卉  冯瑞娥
作者单位:中国医学科学院,北京协和医学院,北京协和医院病理科,北京100730
摘    要:IgG4相关性疾病作为一种全身系统性疾病,可累及多个器官及组织。发生于淋巴结的IgG4相关性淋巴结病由于其临床病理特点缺乏特异性,需与多种病变鉴别,如Castleman’s病样、淋巴滤泡反应性增生、淋巴瘤等。尽管IgG4相关性疾病经激素治疗效果显著,但是某些患者可发展成淋巴瘤。因此有必要提高对IgG4相关性淋巴结病的认识。本文就IgG4相关性淋巴结病的临床及病理组织学等特点进行综述。

关 键 词:IgG4相关性疾病  IgG4相关性淋巴结病  临床病理特点

Clinicopathological features of IgG4-related lymphadenopathy
ZHANG Hui , FENG Rui'e. Clinicopathological features of IgG4-related lymphadenopathy[J]. Journal of International Pathology and Clinical Medicine, 2012, 32(4): 347-351
Authors:ZHANG Hui    FENG Rui'e
Affiliation:ZHANG Hui, FENG Rui’e(Department of Pathology,Peking Union Medical College Hospital;Chinese Academy of Medical Sciences; Peking Union Medical College,Beijing 100730,China)
Abstract:Immunoglobulin G4-related disease(IgG4-RD) is an emerging disease entity of unknown etiology with multiorgan involvement.IgG4-related lymphadenopathy may be easily confused with multicentric Castleman’s disease,follicular hyperplasia,or malignant lymphoma due to its lack of special clinicopathological features.Although IgG4-related lymphadenopathy shows a dramatic response to steroid therapy,some cases may be potentially associated with the development of lymphoma.Thus it is desirable to improve our knowledge of IgG4 related lymphadenopathy.In this review,we summarize the clinicopathological characteristics of IgG4-related lymphadenopathy.
Keywords:IgG4-related disease  IgG4-related lymphadenopathy  clinicopathological features
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