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Increment of brain temporal perfusion during auditory stimulation
Authors:Y. Le Scao  J. L. Baulieu  A. Robier  L. Pourcelot  P. Beutter
Affiliation:(1) Department of Oto-Rhino-Laringology, Centre Hospitalo-universitaire de Tours, 2 boulevard Tonnelle, F-3700 Tours, France;(2) Department of Nuclear Medicine, Centre Hospitalo-universitaire de Tours, 2 boulevard Tonnelle, F-3700 Tours, France
Abstract:A study on the dynamic exploration of the auditory pathway is presented, in which technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography (SPET) was used in volunteers with normal hearing. Changes in 99mTc-HMPAO distribution were calculated using a region of interest/whole-brain count ratio. The results showed a temporal perfusion increment of 17% (right) and 19% (left) during tonal supraliminar stimulation, which was significantly different from the control ROI. Sensitivity tests for the method were requested before any clinical application.Offprint requests to: Y. Le Scao
Keywords:Scintigraphy  Auditory stimulation  Technetium-99m-D,L hexamethylpropylene amine oxine (99mTc-HMPAO)  Temporal cortex
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