不稳定性心绞痛中医证型与HCY、hs—CRP的关系

目的：探讨不稳定性心绞痛中医证型与同型半胱氨酸（HCY）、超敏C反应蛋白（hs—CRP）的关系。方法：不稳定性心绞痛患者102例，测定血清HCY、hs-CRP，行冠脉造影检查，并与同期的非心绞痛患者98例对照。结果：不稳定性心绞痛组HCY及hs—CRP水平明显升高，与对照组比较。差异有显著性意义（P〈0．01）；冠脉病变支数、不同中医证型与HCY及hs—CRP水平亦有显著性差异（P〈0．01），三支病变组〉双支病变组〉单支病变组，心血瘀阻型〉痰浊内阻型〉寒凝心脉型〉心气虚弱型〉心肾阴虚型〉心肾阳虚型。结论：不稳定性心绞痛中医证型间血清HCY、hs—CRP水平存在明显差异（P〈0．05），HCY、hs—CRP可能作为冠心病心绞痛中医辨证分型的客观指标之一。

Relationship Between TCM Syndrome types of Unstable Angina and HCY,hs-CRP

Objective：To investigate the relationship between TCM syndrome types of unstable angina and homecysteine （HCY）, hypersensitive C reactive protein （hs-CRP）. Methods： A total of 102 patients with unstable angina had their serum HCY and hs-CRP determined and underwent coronary angiography. Another 98 subjects served as control group. Results：The levels of HCY and hs-CRP in the angina group were significantly increased compared to the control group（ P 〈 0.01 ）. They were different among varied coronary lesions and TCM syndrome types （ P 〈0.01 ）, the highest level in triplevessel, next double-vessel and then single-vessel coronary lesions, and type of blood stagnation, type of phlegm and turbid stagnation, type of of Chest Stuffiness and Pains, type of Qi weakness, type of heart Yin deficiency, and type of heart Yang deficiency in order. Conclusion：The level of HCY and hs-CRP varies among different TCM syndrome types of angina and can be used as diagnostic markers for the differentiation of TCM syndromes of the coronary disease.