| 中空纤维透析膜的传质研究与模型分析 |
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| 引用本文： | 胡相华,;张立志,;蓝建华,;罗洁伟.中空纤维透析膜的传质研究与模型分析[J].中国医疗器械信息,2014(10):35-39. |
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| 作者姓名： | 胡相华 ;张立志 ;蓝建华 ;罗洁伟 |
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| 作者单位： | [1]国家食品药品监督管理局广州医疗器械质量监督检验中心,广州510080; [2]华南理工大学化学与化工学院,广州510641 |
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| 摘 要： | 中空纤维透析器广泛应用于终末期肾病的血液透析治疗，对全球的肾病患者有着重要作用，然而关于透析器溶质传递方面的研究却很少。本文根据质量守恒定律和双膜理论建立了一个中空纤维透析膜传质模型，使用中小分子代表物质对三种常用膜材料进行测试，并使用该传质模型计算总传质系数和纤维膜的扩散系数，分析纤维膜传质性能与纤维膜材料/结构特性之间的相互关系，为中空纤维膜制备过程中的材料选择、结构优化设计等提出了参考性建议。
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| 关 键 词： | 中空纤维透析膜 传质模型 扩散系数 |
Analysis of Mass-transfer Model in Dialysis Hollow Fiber Membrane |
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| Institution: | HU Xiang-hua, ZHANG Li-zhi, LAN Jian-hua, LUO Jie-wei (1. South China University of Technology (Guangzhou 510641 ) 2 Guangdong Medical Instrumenl Supervision and Test Center of State Food Drug Administration (Guangzhou 510080)) |
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| Abstract: | Hol ow ifber dialyzer is widely applied in the end-stage renal disease in hemo-dialysis therapy. It plays an important role in kidney disease patients in the world. However, there is lit le research of solute transfer in dialyzer. This paper builds a mass-transfer model of dialysis hol ow ifber membrane, based on mass-conservation theory and double-membrane theory. Three common membrane materials are tested and calculated with the mass transfer model with represent solutes. With analysis of relationship between mass-transfer performance and the structural characteristics of membrane, referential suggestions for material selection and structural design in manufacture of hol ow ifber membrane are put forward. |
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| Keywords: | Dialysis hol ow ifber membrane mass transfer model diffusion coefifcient |
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