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Risk assessment and management of new and existing chemicals |
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| Authors: | Van Leeuwen C J Bro-Rasmussen F Feijtel T C Arndt R Bussian B M Calamari D Glynn P Grandy N J Hansen B Van Hemmen J J Hurst P King N Koch R Müller M Solbé J F Speijers G A Vermeire T |
| Affiliation: | a Ministry of Housing, Spatial Planning and the Environment, The Hague, Netherlands b Technical University of Lyngby, Lyngby, Denmark c Procter and Gamble, European Technical Centre, Strombeek-Bever, Belgium d Institute of Occupational Safety and Health, Notification Unit, Dortmund, Germany e Federal Environmental Agency, Berlin, Germany f Laboratory of Ecology, Faculty of Science, University of Milano, Varese, Italy g Commission of the European Communities, DG III Industrial Affairs, Brussels, Belgium h Organization for Economic Co-operation and Development (OECD), Paris, France i Commission of the European Communities, Joint Research Centre, European Chemical Bureau, Ispra, Italy j Netherlands Organization for Applied and Scientific Research (TNO), Zeist, Netherlands k World Wild Fund for Nature, Geneva, Switzerland l , Bucks, UK m Bayer AG, Product Safety Department, Leverkusen, Germany n Federal Research Station, Wädenswil, Switzerland o Unilever Research Port Sunlight Laboratory, Bebington, UK p National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands |
| Abstract: | An evaluation was made of the recently developed risk assessment methodologies for new and existing chemicals in the European Communities. The evaluation also included the methodologies to prioritize chemicals and procedures for risk management, i.e., the (draft) guidance document for the development of strategies for risk reduction. The way in which chemicals are prioritized is accepted with only very few comments. Clear progress has been made in the development and harmonization of risk assessment methodologies and the application of estimation methodologies. Nevertheless, improvements are necessary for the estimation of consumer and occupational exposure, the derivation, use and transparency of assessment factors for chemicals and classes of chemicals based on the mode of toxic action, environmental exposure models and their validation and relation with monitoring data. As far as risk management is concerned it was recommended to improve the integration of the myriad of directives and regulations, to clarify definitions, to provide clear guidance on the determination and weighing of advantages and implications of risk reduction measures and to develop tools, including voluntary agreements, to speed up the slow chemical-by-chemical approach. |
| Keywords: | Risk assessment Risk management New chemical Existing chemical European communities Monitoring Exposure model Occupational exposure Consumer exposure Toxicity Ecotoxicity QSARs Priority setting Risk-benefit analysis Risk reduction |
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