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Facial pain as first manifestation of anti-Hu paraneoplastic syndrome
Authors:Geneviève Demarquay  Adrien Didelot  Véronique Rogemond  Philippe Ryvlin  Michel Gouttard  Paul Garassus  François Mauguière  Jérome Honnorat
Affiliation:1.Service de Neurologie, Hôpital de la Croix-Rousse, 103, Grande Rue de la Croix-Rousse, 69004 Lyon, France ;2.Centre de Référence des Syndromes Paranéoplasiques, Neurological Hospital, Lyon, France ;3.Department of Neurology, Neurological Hospital, Lyon, France ;4.Department of Neurology, Bourg en Bresse Hospital, Bourg en Bresse, France ;5.Department of Neurology, Clinique du Tonkin, Villeurbanne, France
Abstract:The diagnosis of anti-Hu-associated encephalomyelitis/sensory neuropathy may be particularly difficult when cranial nerve involvement represents the first clinical manifestation of the disease. We report a case of a patient who presented with facial pain as the first manifestation of an anti-Hu paraneoplastic syndrome, which needs a rapid detection and treatment of the underlying tumour. We suggest that paraneoplastic neuropathy should be considered during the management of trigeminal neuropathic pain, especially when brain imagery is normal.
Keywords:Paraneoplastic syndrome   Trigeminal neuropathy   Anti-Hu   Cancer   Facial pain
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