Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis |
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Authors: | Zhou Jie Febbraio Maria Wada Taira Zhai Yonggong Kuruba Ramalinga He Jinhan Lee Jung Hoon Khadem Shaheen Ren Songrong Li Song Silverstein Roy L Xie Wen |
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Affiliation: | Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. |
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Abstract: | |
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Keywords: | Acc-1, acetyl CoA carboxylase 1 DTg, double transgenic Fae, long-chain free fatty acid elongase Fas, fatty acid synthase FFA, free fatty acid HA, hemagglutinin LXR, liver X receptor PCN, pregnenolone-16α-carbonitrile PPAR, peroxisome proliferator-activated receptor PXR, pregnane X receptor Scd-1, stearoyl CoA desaturase-1 Srebp, sterol regulatory element-binding protein Tg, transgenic |
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